The blue nevus is a variant of a common mole. It is composed of melanocytes, the cells which produce the melanin pigment, which have a spindled to epithelioid appearance. It presents as a dark blue to black, moderately firm, rounded, sharply defined nodular tumour composed of spindle-shaped melanocytes with slender cytoplasmic processes, occurring often in association with melanin-laden macrophages in a sclerotic dermis. Blue nevi can develop at any age but are usually noticed in second decade of life or later and are twice as common in women as in men. Although rare, malignant degeneration of cellular blue nevi can occur.
Blue Nevi may be inherited as an autosomal dominant trait. Human traits, including the classic genetic diseases, are the product of the interaction of two genes, one received from the father and one from the mother. In dominant disorders, a single copy of the disease gene will be expressed "dominating" the other normal gene and resulting in the appearance of the disease.
In general cases where blue nevi are normal, it usually lingers in the skin and remains unchanged and asymptomatic through out the life of the person. In most cases blue nevi could remain benign for how long they remain and with no known symptoms. Symptoms of blue nevi is to composed of skin and large dilated blood vessels, the nevi do not disappear and are found on internal organs such as the stomach, liver, spleen, heart, bone, muscle, bladder, and vulva. They are easily compressible and refill after compression. Occasionally, the nevi are painful. Ranging in size from millimeters to several centimeters, the nevi can number from a few to hundreds.
Nevi are usually present at birth. Sometimes, however, they may not appear until ages two or three.
No treatment is needed as blue naevi are harmless. However, some people with a blue naevus on an exposed part of the body ask for it to be removed for cosmetic reasons. If the lesion has only recently appeared, your doctor may to prefer to remove it to make sure it is not a dangerous skin cancer, malignant melanoma.
Treatment of Blue Rubber Bleb Nevus primarily involves surgical removal of the hemangioma. Carbon dioxide laser surgery is recommended for removal of external hemangiomas. Removal of internal hemangiomas usually requires conventional surgery. Surgical resection may be recommended to treat growths in the gastrointestinal tract.